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The relationship between Angiotensin converting enzyme gene polymorphism, coronary artery disease, and stent restenosis

December 12, 2005   Categories: New articles  Posted by admin

Patients with diabetes mellitus (DM) have advanced atherosclerosis compared with nondiabetics. Restenosis after intracoronary stent implantation occurs frequently in diabetic patients. Angiotensin II is an important growth factor for the development of neointimal hyperplasia after vascular injury. The aim of our study was to evaluate the relationships between angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and coronary artery disease (CAD) and stent restonosis in diabetic patients.

Published in the  International Heart Journal
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