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New Study Furthers Understanding of the Role of Dual Antiplatelet Therapy in the Prevention Of Atherothrombotic Events, Including Heart Attack, Stroke or Cardiovascular Death in Broad Population

March 15, 2006 Categories: Uncategorized Posted by admin

Results from the CHARISMA (Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance) trial showed that the combination of the antiplatelet agents clopidogrel and aspirin did not demonstrate a statistically significant reduction in the risk of heart attack, stroke or cardiovascular death compared to placebo and aspirin in a broad population of patients with either established atherothrombotic disease or multiple risk factors for atherothrombotic events. Analysis of the two main patient enrollment subgroups revealed different responses to clopidogrel and aspirin therapy.

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