PTCA.us – Angioplasty and stenting digest.

Effects of local gene transfer of VEGF on neointima formation after balloon injury in hypercholesterolemic rabbits

February 10, 2006   Categories: New articles  Posted by admin

Enhancement of the generation of nitric oxide (NO) and vascular endothelial growth factor (VEGF) are suggested to prevent restenosis after angioplasty. Accordingly, authors tested whether the local delivery of L-arginine (L-Arg), a substrate for NO generation and the VEGF gene, alone or in combination, can influence neointima formation in hypercholesterolemic rabbits.

Abstract